When to take Vagifem® 10 mcg.

For the first 2 weeks, you’ll use Vagifem® (estradiol vaginal inserts) 10 mcg once daily. After that, you’ll reduce to twice a week, as directed by your health care provider.

You choose the days you take Vagifem® 10 mcg. For example, you could take it every Tuesday and Friday, as shown in the dosing schedule below. You can use Vagifem® 10 mcg at any time of the day that you choose, but it should be done at the same time on each dosing day.

Vagifem® 10 mcg dosing schedule

  S M T W T F S
starting out
week 1:
1 Vagifem® 10 mcg insert every day
week 2:
1 Vagifem® 10 mcg insert every day
  S M T W T F S
going forward
week 3 and beyond:
1 Vagifem® 10 mcg insert twice a week; for example, Tuesday and Friday